April and Jackson are trying to figuring out their relationship, but eventually break up.Cristina comes back to Seattle when her mentor in Minnesota dies.Callie tries to come up with a plan to guarantee a full recovery for Derek's hand.Callie is supportive to Arizona who had to have her leg amputated, but Arizona is not happy that Callie made the call to amputate her leg.Cristina flees from Seattle and takes a job in Minnesota.Meredith mourns Lexie and is supportive to Derek, who may never operate again.Mark Sloan dies after he's taken off of life support.And as Mark prepares to say goodbye, Alex falls for someone new, Cristina tries to rekindle the flame with Owen, and Bailey and Ben discover the perils of a long-distance relationship. Meredith finds her groove in the operating room while Derek's hand injury forces him to focus on something other than surgery. But from the ashes, romance will rise, with each surgeon handling the loss in their own personal way. The plane crash that took the lives of Lexie Grey and Mark Sloan sent shockwaves throughout the hospital. It's a year of bold new beginnings as your favorite doctors return to Seattle Grace for the biggest challenge of their lives.
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